Vanadate-Induced Renal cAMP and Malondialdehyde Accumulation Suppresses Alpha 1 Sodium Potassium Adenosine Triphosphatase Protein Levels
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چکیده
منابع مشابه
Renal sodium-potassium-activated adenosine triphosphatase and sodium reabsorption.
The role of renal Na(+),K(+)-ATPase in sodium reabsorption was further examined in dogs in which digoxin, a specific inhibitor of the enzyme system, was infused into one renal artery in doses ranging from 0.4 to 0.9 mug/kg/min (low dose) and from 1.0 to 4.0 mug/kg/min (high dose). A significant natriuresis occurred with both dose ranges which was accompanied by inhibition of Na(+),K(+)-ATPase o...
متن کاملModulation of Renal Sodium-Potassium-Adenosine Triphosphatase by Aldosterone
The purpose of this study was to determine the nephron site, time course, and mechanism of mineralocorticoid action on renal tubular Na-K-ATPase in rats and rabbits, without dietary manipulation and by using the natural mineralocorticoid aldosterone. Sustained, high physiologic levels of circulating aldosterone mimicking those produced endogenously during potassium loading or sodium deprivation...
متن کاملDistribution of lens sodium-potassium-adenosine triphosphatase.
PURPOSE The specific activity of sodium-potassium-adenosine triphosphatase (Na-K-ATPase) in lens fiber cells is lower than the specific activity in lens epithelium. To test whether there is a reduction in the expression of Na-K-ATPase molecules in lens fibers, a Western blot technique was used. METHODS Membrane material was isolated from different regions of the rabbit lens. Na-K-ATPase (aden...
متن کاملRenal adaptation to potassium in the adrenalectomized rabbit. Role of distal tubular sodium-potassium adenosine triphosphatase.
Potassium secretion and sodium-potassium adenosine triphosphatase (Na-K-ATPase) activity in the distal nephron segments are known to be influenced by the dietary intake of K+. This has been attributed to a change in the plasma aldosterone level, which also influences K+ secretion and Na-K-ATPase activity in the distal nephron. To investigate whether or not dietary K+ can modulate Na-K-ATPase ac...
متن کاملSodium- potassium-activated adenosine triphosphatase and osmotic regulation by fishes.
JAMPQL, LEE M., AND FRANKLIN H. EPSTEIN. Sodiumpotassiumactivated adenosine triphosphatase and osmotic regulation by fishes. Am. J. Physiol. 218(2) : 607-611. 1970.-The specific activity of sodiumpotassium-activated adenosine triphosphatase is high in the gills of sa1twater teleosts, and low in the gills of elasmobranchs and freshwater teleosts. The activity of NaK-ATPase in gill filaments and ...
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ژورنال
عنوان ژورنال: Toxicological Research
سال: 2018
ISSN: 1976-8257,2234-2753
DOI: 10.5487/tr.2018.34.2.143